TY - JOUR ID - 48667 TI - The Effect of Malva Sylvestris Cream on Episiotomy Pain and Healing: A Randomized Controlled Clinical Trial JO - International Journal of Community Based Nursing & Midwifery JA - IJCBNM LA - en SN - 2322-2476 AU - Mohaghegh, Zaynab AU - Golfakhrabadi, Fereshteh AU - Faal Siahkal, Shahla AU - Dastoorpoor, Maryam AU - Zaheri Abdevand, Zeinab AU - Montazeri, Simin AU - Sharifipour, Foruzan AU - Bahmaei, Hadis AU - Javadnoori, Mojgan AD - Department of Midwifery, School of Nursing and Midwifery, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran; AD - Department of Pharmacognosy, Medicinal Plant Research Center, Faculty of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran; AD - Department of Epidemiology and Biostatistics, Menopause Andropause Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran; AD - Department of Persian Medicine and Pharmacy, Faculty of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran; AD - Reproductive Health Promotion Research Center, Department of Midwifery, School of Nursing and Midwifery, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran AD - Department of Midwifery, Ahwaz Jundishapur University of Medical Sciences Y1 - 2022 PY - 2022 VL - 10 IS - 4 SP - 248 EP - 258 KW - Episiotomy KW - Malva KW - Pain KW - Wound healing DO - 10.30476/ijcbnm.2022.95772.2082 N2 - Background: Episiotomy is one of the common procedures during childbirth in Iran, which causes pain, discomfort, and scar in the perineum. This study aimed to pursue the effect of Malva Sylvestris cream on episiotomy pain and healing.Methods: This study was a double-blinded randomized-controlled clinical trial that was conducted from April to December 2021 at the Sina hospital in Ahvaz, Iran. Sixty women were selected and randomly assigned to control and intervention groups using block randomization. The main outcomes included pain assessment and episiotomy wound healing that are assessed by the Visual analog scale (VAS), and perineal healing scale included redness, edema, ecchymosis/bruising, discharge, approximation (REEDA). The cream was used twice a day for up to 14 days. The participants were followed on the first, seventh, and fourteenth days postpartum. Independent T-test, Mann-Whitney, and Chi-square, and Generalized Estimating Equations (GEE) model were used by SPSS software version 22 for data analysis. Statistically significant level was considered less than 0.05.Results: There were no significant statistical differences between the two groups in demographic characteristics (P>0.05). No significant statistical differences were found in both groups in terms of perineal healing (B=-0.05; P=0.89) and pain scores (B=0.15; P=0.56). However, the chance of external dysuria in the intervention group decreased by 77% (P=0.01).Conclusion: Despite showing the positive effect of Malva Sylvestris extract on wound healing in animal and in-vitro studies, this clinical study failed to show the positive effect of this extract on wound healing and pain relief of episiotomy. However, future clinical trials are needed to substantiate the above findings.Trial Registration Number: IRCT20190826044621N1. UR - https://ijcbnm.sums.ac.ir/article_48667.html L1 - https://ijcbnm.sums.ac.ir/article_48667_0d84687bfbf1c871b1d2e8b76a78bf6a.pdf ER -