Document Type : Original article
Authors
1
International Branch of Shahid Beheshti, University of Medical Sciences, Tehran, Iran
2
Department of Midwifery and Reproductive Health, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran
3
Department of Pharmacognosy, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran
4
Department of Paramedical, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran
5
Razi Herbal, Medicines Research Center, Lorestan University of Medical Sciences, Lorestan, Iran
6
Department of Paramedical, School of Medicine, Jundishapur University of Medical Sciences, Ahvaz, Iran
7
Department of Paramedical, Islamic Azazd University Borojerrd Branch, Borojerrd, Iran
8
Department of Nursing and Midwifery, School of Nursing and Midwifery, Isfahan University of Medical Sciences. Isfahan, Iran
9
National Nutrition and Food Technology Research Institute, Department of the International Affairs of Shahid Beheshti University of Medical Sciences, Tehran, Iran
Abstract
Background: The present study was conducted on the effect of prangos ferulacea vaginal cream on accelerating the recovery of bacterial vaginosis.Methods: This randomized controlled clinical trial was conducted on 100 non-pregnant women referring to health centers affiliated to Lorestan University of Medical Sciences in 2016 with the diagnosis of bacterial vaginosis based on the patient’s complaints, Amsel’s clinical criteria, and the Nugent microscopic criteria. The women were randomly divided into two groups of 50. One group was treated with oral metronidazole plus Prangos ferulacea vaginal cream and the other with oral metronidazole plus a placebo vaginal cream for seven days. The patient’s complaints, Amsel’s clinical criteria and the Nugent microscopic criteria were assessed seven days after treatment. The data were analyzed using SPSS, version 20, with a significance level of 0.05.Results: The response to oral metronidazole plus Prangos ferulacea vaginal cream treatment was 94% according to Amsel’s clinical criteria and 88% according to the Nugent microscopic criteria. The response to oral metronidazole plus placebo vaginal cream treatment was 94% according to Amsel’s criteria and 86% according to the Nugent criteria. The analysis of the patients’ complaints, Amsel’s clinical criteria and the Nugent microscopic criteria showed significant differences in each group before and after the treatment.Conclusion: This trial showed that Prangos ferulacea vaginal cream accelerated the recovery of bacterial vaginosis of patients with bacterial vaginosis. It can be used effectively as a complementary treatment with oral metronidazole in cases of medication resistance and also in people wishing to use herbal remediesTrial Registration Number: IRCT2016042327534N1
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