Knowledge and Uptake of Human Papilloma Virus Vaccine among Female Undergraduate Students in North-Central, Nigeria: A Cross- Sectional Study

Document Type : Original Article

Authors

1 Department of Nursing Sciences, Faculty of Clinical Sciences, College of Health Sciences, University of Ilorin, Nigeria;

2 Faculty of Nursing Sciences, College of Health Sciences, Bowen University, Iwo, Nigeria

10.30476/ijcbnm.2025.102762.2509

Abstract

Background: Human Papilloma Virus (HPV) vaccine is the most effective measure against HPV
infection. Therefore, the study aimed at assessing knowledge and uptake of HPV vaccine among
female undergraduates in North-Central, Nigeria.
Methods: A cross-sectional research design was conducted from March-April 2023 among female
undergraduate students and a convenience sampling technique was used to select 380 respondents
for the study. A self-administered questionnaire was used for data collection. Data analysis was done
using SPSS version 26. Chi-square test was used to test the association between sociodemographic
variables, knowledge, and uptake of HPV vaccine. Prediction of uptake of HPV vaccine according to
sociodemographic variables and knowledge was done using binary logistic regression test. P-value less
than 0.05 was considered statistically significant.
Results: Most of the respondents were between 20 and 25 years and were sexually inactive. The
results shows that most of the respondents (68.2%) had low knowledge, and only 15% had received the
HPV vaccine; of them, 7.6% had completed the doses of the HPV vaccine. Age 20-25 years (β=0.865,
P=0.003), 3rd year (β=0.520, P<0.001) and 4th year (β=0.005, P<0.001) of study, sexual activity (β=0.545,
P<0.001), multiple sexual partners as 3-4 partners (β=2.454, P<0.001) and 5-6 partners (β=0.576,
P<0.001), prior STIs history (β=0.545, P=0.035), and low knowledge level (β=0.362, P<0.001) were
predictors of HPV vaccine uptake.
Conclusion: Understanding predictor factors of HPV vaccination uptake can help to design better
public health interventions to improve HPV vaccine coverage among female undergraduate students
in Nigeria.

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